CAS Number: 147600-40-6Molecular Weight: 384.27Salt Form: TFAPurity: >90%Sequence (3-letter): Ac-Leu-Val-Lys-CHOSequence (1-letter): Ac-LVK-CHOStorage: -20 °C or below
Ac-Leu-Val-Lys-CHO is a potent reversible peptidyl aldehyde inhibitor of Cathepsin B (IC₅₀ = 4 nM). Cathepsin B is a lysosomal cysteine protease with a role in intracellular protein degradation. Cathepsin B crosses the blood-brain barrier and elevated levels are implicated in many neurological maladies including traumatic brain injury, epilepsy, and Alzheimer’s disease.
Categories | Peptides |
---|
Filter | Inhibitor |
---|